Dual x-ray absorptiometry monitoring in pediatric short bowel syndrome: an integrative review / Monitorização por absortometria com duplo raio X na síndrome do intestino curto pediátrica: uma revisão integrativa

ABSTRACT Objective: To analyze the bone health of pediatric patients with short bowel syndrome intestinal failure (SBS-IF). Data source: An integrative literature review was performed using the data published in the MEDLINE-PubMed and Scientific Electronic Library Online (SciELO) databases between January 2010 and April 2021, and through a manual search of the reference lists of relevant studies. Studies were included if they assessed bone mineral density by the Dual X-Ray Absorptiometry (DXA) technique, incorporated pediatric patients (up to 20 years of age) with SBS under parenteral nutrition (PN) and were written in English. Eleven primary sources met the inclusion criteria for this study. Data synthesis: Pediatric patients with SBS-IF under long-term parenteral nutrition experienced frequent changes in bone metabolism, leading to osteoporotic fractures and growth failure. These patients have deficiencies in multiple nutrients, such as calcium, magnesium, phosphorus, and vitamin D. Consequently, there are variations in the secretion and regulation of the parathyroid hormone. In addition, the pharmacotechnical limitations related to calcium and phosphorus in the PN solution, use of glucocorticoids, and difficulty performing physical activity are risk factors for the development of metabolic bone disease in pediatric patients with SBS-IF. Conclusions: Low bone mineral density was associated with a high risk of developing osteoporosis, fractures, and growth deficiency in pediatric patients with SBS-IF on PN therapy in the long term.

Objetivo: Analisar a saúde óssea de pacientes pediátricos com síndrome do intestino curto — falência intestinal (SIC-FI). Fontes de dados: Revisão integrativa da literatura usando os dados publicados nas bases de dados Medical Literature Analysis and Retrieval System Online/ United States National Library of Medicine (MEDLINE/PubMed) e Scientific Electronic Library Online (SciELO) entre janeiro de 2010 e abril de 2021 e por meio de busca manual nas listas de referências de estudos relevantes. Foram incluídos estudos em inglês que avaliaram a densidade mineral óssea pela técnica de absorciometria de raio X duplo (DXA), incluíram pacientes pediátricos (até 20 anos de idade) com SIC sob terpia nutricional parenteral. Onze fontes primárias preencheram os critérios de inclusão para este estudo. Síntese dos dados: A pesquisa revelou que pacientes pediátricos com SIC-FI sob nutrição parenteral (NP) de longo prazo tiveram alterações frequentes no metabolismo ósseo, levando a fraturas osteoporóticas e falha de crescimento. Esses pacientes apresentam deficiências de múltiplos nutrientes, como cálcio, magnésio, fósforo e vitamina D. Consequentemente, houve variações na secreção e regulação do hormônio da paratireoide. Além disso, as limitações farmacotécnicas relacionadas ao cálcio e fósforo na solução de NP, o uso de glicocorticoides e dificuldade para realizar atividade física são fatores de risco para o desenvolvimento de doença óssea metabólica em pacientes pediátricos com SIC-FI. Conclusões: A baixa densidade mineral óssea foi associada a um alto risco de desenvolver osteoporose, fraturas e deficiência de crescimento em pacientes pediátricos com SIC-FI sob terapia nutricional parenteral em longo prazo.

Correlation of BUA, SOS, T-score and SI with bone mineral density in elderly women with knee osteoarthritis and their diagnostic efficacy in osteoporosis / 中国医师杂志

Objective:To analyze the broadband ultrasound attenuation (BUA), speed of sound (SOS), standard deviation of bone density (T-Score) and stiffness index (SI) with bone mineral density (BMD) in elderly female patients with knee osteoarthritis and their diagnostic efficacy of osteoporosis.Methods:Fifty elderly female patients with knee osteoarthritis admitted o Tangshan People′s Hospital from January 2021 to January 2022 were selected as the observation group, and 40 healthy female patients during the same period were selected as the control group. The results of BUA, SI, T-score and SOS in observation group and control group were analyzed and compared. The BUA, SI, T-score and SOS in elderly women with knee osteoarthritis at different ages and with different bone densities were compared, and the diagnostic value of BUA, SI, T-score and SOS in osteoporosis was analyzed by receiver operating characteristic (ROC) curve.Results:The BUA, SI and T-score of observation group were lower than that in the control group, while SOS was higher than that in the control group (all P<0.05). Among elderly female patients with knee osteoarthritis of different ages, the older the age, the lower the BUA, SI and T-score (all P<0.05), while there was no statistical significance in SOS of elderly female patients with knee osteoarthritis of different ages ( P>0.05). In elderly women with knee osteoarthritis with different BMD grades, the BUA, SI, and T-score in the osteoporosis group were lower than those in the osteopenia group and the normal bone group, and the BUA, SI, and T-score in the osteopenia group were lower than those in the normal bone group; the SOS in the osteoporosis group was higher than those in the osteopenia group and the normal bone group, and the SOS in the osteopenia group was higher than those in the normal bone group (all P<0.05). BUA, SOS, T-score and SI had high sensitivity and specificity in the diagnosis of osteoporosis in elderly women with knee osteoarthritis (all P<0.05). Conclusions:BMD in elderly women with knee osteoarthritis is associated with BUA, SI, T-score, and SOS, and has high diagnostic value for osteoporosis.

Hounsfield units use in spinal surgery planning: systematic review and meta-analysis / Uso das unidades hounsfield no planejamento da cirurgia espinhal: revisão sistemática e meta-análise / Uso de las unidades hounsfield en la planificación de la cirugía espinal: revisión sistemática y metanálisis

ABSTRACT Bone mineral density is a crucial factor in the success or failure of osteosynthesis in spine surgery; it shows the onset of osteoporosis and related complications. Its evaluation is verified by dual-energy X-ray absorptiometry (DEXA) and Hounsfield Unit (HU) measurement by CT scan. Objective: Determine the use of HU in surgical planning; compare utility in diagnosing osteoporosis by DEXA; and evaluate sensitivity in predicting complications. Method: A systemic literature review was conducted on PubMed, in line with PRISMA methodology. Including those who justified the use of pre-surgical planning, compared HU/DEXA, and assessed complications. For the statistical analysis, the χ2 was used. Results: 57 articles were identified by selecting nine that met the inclusion criteria. In patients undergoing spinal surgery for fixation and fusion for degenerative pathology, HU measurement showed a prevalence of osteoporosis of 58.5% (sensitivity 93.26%; specificity 90.22%), osteoporosis-associated complications of 24.5%, proper diagnosis of 71.98%, and screw release rate of 82.31%. Conclusions: UH measurement for the diagnosis of osteoporosis turns out to be more sensitive, specific, and predictive compared to DEXA, especially in elderly patients; it represents a useful tool in planning spinal surgery, minimizing the risk of complications such as screw release, fractures, pseudoarthrosis, subsidence of intersomatic devices, and kyphosis of the proximal junction. Level of evidence II; Study Design: Systematic Review and meta-analysis.

RESUMO: A densidade mineral óssea é um fator crucial no sucesso ou falha da osteossíntese na cirurgia da coluna vertebral; isso mostra o aparecimento da osteoporose e complicações relacionadas a ela. Sua avaliação é verificada por absorptiometria de raios-X de dupla energia (DEXA) e medição da Unidade Hounsfield (HU) por tomografia. Objetivo: Determinar o uso do HU no planejamento cirúrgico; comparar utilidade no diagnóstico de osteoporose pelo DEXA; e avaliar a sensibilidade na previsão de complicações. Método: Foi realizada uma revisão de literatura sistêmica no PubMed, em consonância com a metodologia PRISMA. Incluindo aqueles que justificaram o uso do planejamento pré-cirúrgico, comparou o HU/DEXA e avaliaram complicações. Para a análise estatística, o χ2 foi usado. Resultados: Inicialmente foram identificados 57 artigos por meio da seleção de nove que atenderam aos critérios de inclusão. Em pacientes submetidos à cirurgia espinhal para fixação e fusão por patologia degenerativa, a medição do HU apresentou prevalência de osteoporose de 58,5% (sensibilidade 93,26%; especificidade 90,22%), complicações associadas à osteoporose de 24,5%, diagnóstico adequado de 71,98% e taxa de liberação de parafusos de 82,31%. Conclusões: A medição da UH para o diagnóstico da osteoporose acaba sendo mais sensível, específica e preditiva em relação ao DEXA, principalmente em pacientes idosos; representa uma ferramenta útil no planejamento da cirurgia espinhal, minimizando o risco de complicações como liberação de parafusos, fraturas, pseudoartrose, subsidência de dispositivos intersomáticos e cifose da junção proximal. Nível de evidência II; Revisão Sistemática e meta-análise.

RESUMEN: La densidad mineral ósea es un factor crucial en el éxito o fracaso de la osteosíntesis en la cirugía espinal; esto muestra la aparición de osteoporosis y las complicaciones relacionadas con ella. Su evaluación se verifica mediante absorciometría de rayos X de energía dual (DEXA) y medición unitaria de Hounsfield (HU) por tomografía. Objetivo: Determinar el uso de HU en la planificación quirúrgica; comparar la utilidad en el diagnóstico de osteoporosis por DEXA; y evaluar la sensibilidad en la predicción de complicaciones. Método: Se realizó una revisión sistémica de la literatura en PubMed, en línea con la metodología PRISMA. Incluyendo aquellos que justificaron el uso de la planificación prequirúrgica, compararon HU/DEXA y evaluaron las complicaciones. Para el análisis estadístico se utilizó χ2. Resultados: Inicialmente se identificaron 57 artículos seleccionando 9 que cumplían con los criterios de inclusión. En pacientes sometidos a cirugía espinal por fijación y fusión por patología degenerativa, la medición de HU mostró una prevalencia de osteoporosis del 58,5% (sensibilidad 93,26%; especificidad 90,22%), complicaciones asociadas a osteoporosis del 24,5%, diagnóstico adecuado del 71,98% y tasa de liberación de tornillo del 82,31%. Conclusiones: La medición de la UH para el diagnóstico de osteoporosis resulta ser más sensible, específica y predictiva en comparación con el DEXA, principalmente en pacientes de edad avanzada; representa una herramienta útil en la planificación de la cirugía espinal, minimizando el riesgo de complicaciones como la liberación del tornillo, fracturas, pseudoartrosis, hundimiento de dispositivos intersomáticos y cifosis de la unión proximal. Nivel de evidencia II; Revisión sistemática y meta-análisis.

Correlation between body composition data obtained by DXA and skinfold predictive protocols in sprinters / Correlação entre dados de composição corporal obtidos pelo DXA e protocolos preditivos de dobras cutâneas em velocistas

Abstract The aim of this study was to describe the correlation between body composition data obtained through DXA and through skinfolds strategy, with some of their respective formulas, in sprinters. The sample consisted of 15 male sprinters (23.81 years ± 3.11; 70.06 Kg ± 4.38; and 179.13 CM ± 5.16) all high performance runners of speed and barriers events (100m, 200m, 400m, 110m with barriers and 400m with barriers). The athletes were submitted to DXA evaluation procedure and to skinfolds collection (triceps, biceps, subscapular, supra iliac, abdominal, medial thigh and calf) and the results were calculated through four distinct equations: Slaughter, Faulkner, Lázari and Boileau. The respective DXA correlations (0.60; 0.81; 0.23 and 0.48) and the equations predicted by skinfold strategy were calculated using Pearson correlation. Among the equations used, Faulkner's was the one presenting highest correlation value when compared to DXA protocol, although all of them aimed to estimate values for BF%.

Resumo O objetivo deste estudo foi descrever a correlação entre dados de composição corporal obtidos através de DEXA, e pela estratégia de dobras cutâneas, com algumas de suas respectivas fórmulas, em velocistas. A amostra foi composta por 15 velocistas do sexo masculino (23,81 anos ± 3,11; 70,06 Kg ± 4,38; e 179,13 cm ± 5,16) todos corredores de alto desempenho das provas de velocidade e barreiras (100m, 200m, 400m, 110m com barreiras e 400m com barreiras). Os atletas foram submetidos ao procedimento de avaliação do DEXA e a coleta de dobras cutâneas (tricipital, bicipital, subescapular, supra ilíaca, abdominal, coxa medial e panturrilha) e os resultados calculados através de quatros distintas equações Slaughter, Faulkner, Lázari e Boileau. As respectivas correlações (0,60; 0,81; 0,23 e 0,48) de DEXA e as equações previstas pela estratégia de dobras cutâneas foram calculadas através da correlação de Pearson. Dentre as equações utilizadas, a de Faulkner foi a que apresentou maior valor de correlação quando comparada ao protocolo do DEXA, apesar de todas terem por objetivo estimar valores para o %G.

Comparison of bone parameters by body region in university athletes: systematic review / Comparación de parámetros óseos por región corporal en atletas universitarios: revisión sistemática / Comparação dos parâmetros ósseos por região corporal em atletas universitários: revisão sistemática

ABSTRACT Introduction: Bone mineral density (BMD) and bone mineral content (BMC) vary depending on the type of sport practiced and the body region, and their measurement can be an effective way to predict health risks throughout an athlete's life. Objective: To describe the methodological aspects (measurement of bone parameters, body regions, precision errors and covariates) and to compare BMD and BMC by body region (total body, upper limbs, lower limbs and trunk) among university athletes practicing different sports. Methods: A search was performed on the databases PubMed, Web of Science, Scopus, ScienceDirect, EBSCOhost, SportDiscus, LILACS and SciELO. Studies were selected that: (1) compared BMD and BMC of athletes practicing at least two different sports (2) used dual-energy X-ray absorptiometry (DXA) to assess bone parameters (3) focused on university athletes. The extracted data were: place of study, participant selection, participants' sex, sport practiced, type of study, bone parameters, DXA model, software used, scan and body regions, precision error, precision protocol, covariates and comparison of bone parameters between different sports by body region. Results: The main results were: 1) BMD is the most investigated bone parameter; 2) total body, lumbar spine and proximal femur (mainly femoral neck) are the most studied body regions; 3) although not recommended, the coefficient of variation is the main indicator of precision error; 4) total body mass and height are the most commonly used covariates; 5) swimmers and runners have lower BMD and BMC values; and 6) it is speculated that basketball players and gymnasts have greater osteogenic potential. Conclusions: Swimmers and runners should include weight-bearing exercises in their training routines. In addition to body mass and height, other covariates are important. The results of this review can help guide intervention strategies focused on preventing diseases and health problems during and after the athletic career. Level of evidence II; Systematic Review.

RESUMEN Introducción: La densidad mineral ósea (DMO) y el contenido mineral óseo (CMO) varían en función del deporte practicado y de la región corporal, y su medición puede ser una forma efectiva de predecir los riesgos para la salud a lo largo de la vida de un atleta. Objetivo: Describir los aspectos metodológicos (medición de parámetros óseos, regiones corporales, errores de precisión y covariables) y comparar la DMO y el CMO por región corporal (cuerpo total, miembros superiores, miembros inferiores y tronco) en atletas universitarios de diferentes deportes. Métodos: La búsqueda se realizó en las bases de datos PubMed, Web of Science, Scopus, ScienceDirect, EBSCOhost, SportDiscus, LILACS y SciELO. Se seleccionaron estudios que: (1) compararon la DMO y el CMO de atletas que practicaban al menos dos deportes; (2) utilizaron la absorciometría de rayos X de doble energía (DXA) para evaluar los parámetros óseos y (3) se centraron en atletas universitarios. Los datos extraídos fueron: ubicación del estudio, selección de los participantes, sexo de los participantes, deporte practicado, tipo de estudio, parámetros óseos, modelo de DXA, software utilizado, escaneo y regiones corporales, error de precisión, protocolo de precisión, covariables y comparación de parámetros óseos entre deportes por región corporal. Resultados: Los principales resultados fueron: 1) DMO como el parámetro óseo más investigado; 2) cuerpo total, columna lumbar y parte proximal del fémur (principalmente cuello femoral) como las regiones corporales más estudiadas; 3) aunque no se recomienda, el coeficiente de variación fue el principal indicador de error de precisión; 4) la masa corporal total y la altura fueron las covariables más utilizadas; 5) los nadadores y corredores presentan valores más bajos de DMO y CMO; 6) se especula un mayor potencial osteogénico en jugadores del baloncesto y gimnastas. Conclusiones: Los nadadores y corredores deben incluir ejercicios con pesas en su rutina de entrenamiento. Además de la masa corporal y la altura, otras covariables son importantes. Los resultados de esta revisión pueden guiar las estrategias de intervención centradas en la prevención de enfermedades y problemas de salud durante y después de la carrera deportiva. Nivel de evidencia II, Revisión Sistemática.

RESUMO Introdução: A densidade mineral óssea (DMO) e o conteúdo mineral ósseo (CMO) variam dependendo do esporte praticado e região corporal, e sua medição pode ser uma forma eficaz de prever riscos para a saúde ao longo da vida de um atleta. Objetivo: Descrever os aspectos metodológicos (mensuração dos parâmetros ósseos, regiões corporais, erros de precisão e covariáveis) e comparar a DMO e o CMO por região corporal (corpo total, membros superiores, membros inferiores e tronco) em atletas universitários de diferentes modalidades esportivas. Métodos: A busca foi realizada nos bancos de dados PubMed, Web of Science, Scopus, ScienceDirect, EBSCOhost, SportDiscus, LILACS e SciELO. Foram selecionados estudos que: (1) compararam a DMO e o CMO de atletas que praticam pelo menos dois esportes; (2) usaram absorciometria de raios X de dupla energia (DXA) para avaliar os parâmetros ósseos e (3) com foco em atletas universitários. Os dados extraídos foram local do estudo, seleção dos participantes, sexo dos participantes, esporte praticado, tipo de estudo, parâmetros ósseos, modelo DXA, software utilizado, varredura e regiões corporais, erro de precisão, protocolo de precisão, covariáveis e comparação de parâmetros ósseos entre esportes por região do corpo. Resultados: Os principais resultados foram: 1) DMO como parâmetro ósseo mais investigado; 2) corpo total, coluna lombar e parte proximal do fêmur (principalmente colo do fêmur) como as regiões corporais mais estudadas; 3) embora não seja recomendado, o coeficiente de variação foi o principal indicador de erro de precisão; 4) massa corporal total e estatura como covariáveis mais usadas; 5) nadadores e corredores têm valores mais baixos de DMO e CMO e 6) especula-se que jogadores de basquete e ginastas têm maior potencial osteogênico. Conclusões: Nadadores e corredores devem incluir exercícios de sustentação de peso na rotina de treinamento. Além da massa corporal e da estatura, outras covariáveis são importantes. Os resultados desta revisão podem ajudar a orientar estratégias de intervenção focadas na prevenção de doenças e problemas de saúde durante e depois da carreira esportiva. Nível de evidência II, Revisão sistemática.

The disparity of measuring bone mineral content using bioimpedance and dual-energy absorptiometry in the context of hyperparathyroidism / A disparidade nos valores do conteúdo mineral ósseo medido usando bioimpedância e absorciometria de dupla energia no contexto do hiperparatireoidismo

Abstract Introduction: Body composition is critical for the evaluation of patients with Chronic Kidney Disease (CKD) and can be obtained from either multifrequency bioelectrical impedance analysis (BIA) or dual-energy absorptiometry (DXA). Although the discrepancy between the results obtained from both methods has already been described, reasons are unknown, and might be related to secondary hyperparathyroidism, which is associated with bone loss. Methods: We have evaluated 49 patients (25 males and 24 females): 20 with CKD not on dialysis and 29 on maintenance hemodialysis [18 with severe hyperparathyroidism (HD-SHPT) and 11 submitted to parathyroidectomy (HD-PTX)]. All patients underwent DXA and BIA. Results: The median age and body mass index (BMI) were 49 years and 25.6 kg/m2, respectively. Patients exhibited low bone mineral content (BMC) measured by DXA, particularly those from the HD-SHPT group. The largest BMC measurement disagreement between DXA and BIA was found in the HD-SHPT group (p=0.004). Factors independently associated with this discrepancy in BMC measurement were serum phosphate (p=0.003) and patient group (p=0.027), even after adjustments for age, BMI, and gender (adjusted r2=0.186). PTX attenuated this difference. Discussion: BIA should be interpreted with caution in patients with SHPT due to a loss of accuracy, which can compromise the interpretation of body composition.

Resumo Introdução: A composição corporal é fundamental para a avaliação de pacientes com Doença Renal Crônica (DRC), e pode ser obtida por análise de impedância bioelétrica por multifrequência (BIA) ou absorciometria de dupla energia (DXA). Embora a discrepância entre os resultados obtidos pelos dois métodos já tenha sido descrita, os motivos são desconhecidos e podem estar relacionados ao hiperparatireoidismo secundário, devido à perda óssea. Métodos: Avaliamos 49 pacientes (25 homens e 24 mulheres): 20 com DRC não em diálise e 29 em hemodiálise de manutenção [18 com hiperparatireoidismo grave (HD-SHPT) e 11 submetidos à paratireoidectomia (HD-PTX)]. Todos os pacientes foram submetidos à DXA e BIA. Resultados: A mediana da idade e do índice de massa corporal (IMC) foram de 49 anos e 25,6 kg/m2, respectivamente. Os pacientes exibiram baixo conteúdo mineral ósseo (CMO) medido pelo DXA, particularmente aqueles do grupo HD-SHPT. A maior discordância da medida do CMO entre DXA e BIA foi encontrada no grupo HD-SHPT (p = 0,004). Os fatores independentemente associados a essa discrepância na medida do CMO foram fosfato sérico (p = 0,003) e grupo de pacientes (p = 0,027), mesmo após ajustes para idade, IMC e sexo (r2 ajustado = 0,186). PTX atenuou essa diferença. Discussão: A BIA deve ser interpretada com cautela em pacientes com HPTS devido a uma perda de precisão, o que pode comprometer a interpretação da composição corporal.

Concurrent validity of five prediction equations to evaluate fat percentage in a sports group expected to yield high performance from Medellín, Colombia / Validez concurrente de cinco ecuaciones de predicción para evaluar el porcentaje de grasa en un grupo de deportistas con expectativas de alto rendimiento de Medellín, Colombia

Abstract | Introduction: No equations to predict the body composition of athletes from Medellín expected to have high performance have been constructed and, thus, decisions regarding their training and nutrition plans lack support. Objective: To calculate the concurrent validity of five prediction equations for fat percentage in a group of athletes from Medellín, Colombia, expected to yield high performance. Materials and methods: We conducted a cross-sectional analysis to validate diagnostic tests using secondary-source data of athletes under the age of 18 who were part of the "Medellín Team'.' The gold standard was dual-energy X-ray densitometry (DEXA). We analyzed the Slaughter, Durnin and Rahaman, Lohman, and Johnston prediction equations, as well as the five-component model. We used the intraclass correlation coefficient to assess the consistency of the methods and the Bland-Altman plot to calculate the average bias and agreement limits of each of the equations. Results: We included 101 athletes (50,5 % of them women). The median age was 14,8 years (IR: 13,0 - 16,0). The concurrent validity was "good/excellent" for the Johnston and the Durnin and Rahaman equations and the five-components model. The Lohman equation overestimated the fat percentage in 12,7 points. All of the equations showed broad agreement limits. Conclusions: The Durnin and Rahaman and the Johnston equations, as well as the five-component model, can be used to predict the FP in the study population as they showed a "good/excellent" concurrent validity and a low average bias. The equations analyzed have low accuracy, which hinders their use to diagnose the individual fat percentage within this population.

Resumen | Introducción. La falta de ecuaciones de predicción de la composición corporal de deportistas con expectativas de alto rendimiento en Medellín dificulta la toma de decisiones para su entrenamiento y nutrición. Objetivo. Calcular la validez concurrente de cinco ecuaciones de predicción del porcentaje de grasa en un grupo de deportistas con expectativas de alto rendimiento en Medellín, Colombia. Materiales y métodos. Se hizo un estudio trasversal de validación de pruebas diagnósticas con datos de una fuente secundaria de deportistas menores de 18 años pertenecientes al "Team Medellín". La densitometría dual de rayos X (DEXA) fue la prueba de referencia. Se analizaron las ecuaciones de predicción de Slaughter, de Durnin y Rahaman, de Lohman y de Johnston, así como el modelo de cinco componentes. Para evaluar la concordancia entre los métodos se utilizó el coeficiente de correlación intraclase y se hicieron análisis de Bland y Altman para calcular el sesgo promedio y los límites de acuerdo de cada una de las ecuaciones. Resultados. Participaron 101 deportistas (50,5 % de ellos mujeres) con una mediana de edad de 14,8 años (RI: 13,0-16,0). La validez concurrente fue "buena-excelente" para las ecuaciones de Johnston, Durnin y Rahaman y el modelo de cinco componentes. La ecuación de Lohman sobreestimó el porcentaje de grasa en 12,7 puntos porcentuales, pero todas mostraron límites de acuerdo amplios. Conclusiones. En la población del estudio se pueden utilizar las ecuaciones de Durnin y Rahaman, la de Johnston y el modelo de cinco componentes para predecir el porcentaje de grasa, pues su validez concurrente fue "buena-excelente" y el sesgo promedio fue bajo. Las ecuaciones que se estudiaron tienen poca precisión, lo que dificulta utilizarlas para el diagnóstico individual del porcentaje de grasa en dicha población.

Swimming and bone mineral density: a sport without osteogenic stimulation? / Natação e densidade mineral óssea: uma modalidade esportiva sem estímulo osteogênico? / Natación y densidad mineral ósea: ¿una modalidad deportiva sin estímulo osteogénico?

ABSTRACT Introduction: The osteogenic effects generated by different sports are the subject of a growing number of research projects. Regular physical activity is one of the main recommendations for the stimulation of bone mineral density (BMD). However, evidence has shown that not all physical activities promote similar effects. In this context, the osteogenic effects of swimming need to be clarified. Objective: To verify and compare total and regional BMD levels between male and female swimming athletes and university non-athletes. Methods: The sample, composed of 60 participants of both sexes, was divided into two groups: 30 swimming athletes (GA): 15 men (22.2 ± 3.92 years; 73.61 ± 16.55 kg; 1.76 ± 0.08 m) and 15 women (21.91 ± 2.21 years; 53.15 ± 8.36 kg; 1.64 ± 0.06 m) and a control group (CG): 30 university non-athletes: 15 men (20.73 ± 1.27 years; 74.4 ± 5.54 kg, 1.74 ± 0.04 m) and 15 women (19.93 ± 2.05 years; 59.72 ± 1.33 kg; 1.63 ± 0.004 m). BMD (total, arms, legs, pelvis and spine) was measured using dual energy X-ray absorptiometry (DXA). The results were compared with one-way ANOVA using Scheffé's post hoc test, when necessary. Results: When compared with the women, the men of both groups presented superior results for all BMD values analyzed. In addition, GA had higher BMD of arms and spine when compared to the CG, both for males (p = 0.016 and p = 0.001, respectively) and females (p = 0.0001 and p = 0.011, respectively). Conclusions: The results of this study demonstrate that young male adults, athletes and non-athletes, present higher levels of BMD than their peers of the opposite sex. In addition, the results suggest that when undertaken for competitive purposes and with a weekly training volume of 12 hours or more, swimming may be beneficial for the bone development of young athletes when compared to non-athlete controls. Level of evidence III; Retrospective comparative study.

RESUMO Introdução: Os efeitos osteogênicos gerados pelas diferentes modalidades esportivas são alvo de um crescente número de investigações. A prática regular de atividades físicas é uma das principais recomendações para a estimulação da densidade mineral óssea (DMO). Entretanto, as evidências têm demonstrado que nem todas as atividades físicas promovem efeitos semelhantes. Nesse contexto, os efeitos osteogênicos da natação precisam ser esclarecidos. Objetivo: Verificar e comparar os níveis de DMO, total e regional, entre atletas de natação de ambos os sexos e universitários não atletas. Métodos: A amostra, composta por 60 participantes de ambos os sexos, foi dividida em dois grupos: 30 atletas de natação (GA): 15 homens (22,2±3,92 anos; 73,61±16,55 Kg; 1,76±0,08 m) e 15 mulheres (21,91±2,21 anos; 53,15±8,36 Kg; 1,64±0,06 m) e um grupo controle (GC): 30 universitários não atletas: 15 homens (20,73±1,27anos; 74,4±5,54 Kg; 1,74±0,04 m) e 15 mulheres (19,93±2,05 anos; 59,72±1,33 Kg; 1,63±0,004 m). As DMO (total, dos braços, pernas, pelve e coluna) foram medidas com utilização da absorciometria radiológica de dupla energia (DXA). Os resultados foram comparados com auxílio da ANOVA One-Way utilizando, quando necessário, o teste post hoc de Scheffé. Resultados: Quando comparados com as mulheres, os homens dos dois grupos apresentaram resultados superiores para todas as DMO analisadas. Além disso, o GA apresentou maiores DMO de braços e de coluna quando comparado ao GC, tanto para homens (p=0,016 e p=0,001, respectivamente) quanto para mulheres (p=0,0001 e p=0,011, respectivamente). Conclusão: Os resultados do presente estudo demonstram que os jovens adultos do sexo masculino, atletas e não atletas, apresentam maiores níveis de DMO que seus pares do sexo oposto. Além disso, os resultados sugerem que, quando praticado com objetivo competitivo e com volume de treinamento semanal igual ou superior a 12 horas, a natação pode ser benéfica para o desenvolvimento ósseo de jovens atletas, quando comparado com o grupo controle não atletas. Nível de evidência III; Estudo retrospectivo comparativo.

RESUMEN Introducción: Los efectos osteogénicos generados por las diferentes modalidades deportivas son objeto de un creciente número de investigaciones. La práctica regular de actividades físicas es una de las principales recomendaciones para la estimulación de la densidad mineral ósea (DMO). Entretanto, las evidencias han demostrado que no todas las actividades físicas promueven efectos semejantes. En ese contexto, los efectos osteogénicos de la natación precisan ser esclarecidos. Objetivo: Verificar y comparar los niveles de DMO, total y regional, entre atletas de natación de ambos sexos y universitarios no atletas. Métodos: La muestra, compuesta por 60 participantes de ambos sexos, fue dividida en dos grupos: 30 atletas de natación (GA): 15 hombres (22,2±3,92 años; 73,61±16,55 Kg; 1,76±0,08 m) y 15 mujeres (21,91±2,21 años; 53,15±8,36 Kg; 1,64±0,06 m) y un grupo control (GC): 30 universitarios no atletas: 15 hombres (20,73±1,27 años; 74,4±5,54 Kg; 1,74±0,04 m) y 15 mujeres (19,93±2,05 años; 59,72±1,33 Kg; 1,63±0,004 m). Las DMO (total, de los brazos, piernas, pelvis y columna) fueron medidas con el uso de la absorciometría radiológica de doble energía (DXA). Los resultados fueron comparados con auxilio de ANOVA One-Way utilizando, cuando fuera necesario, el test post hoc de Scheffé. Resultados: Cuando comparados con las mujeres, los hombres de los dos grupos presentaron resultados superiores para todas las DMO analizadas. Además, el GA presentó mayores DMO de brazos y de columna cuando comparado al GC, tanto para hombres (p=0,016 e p=0,001, respectivamente) como para mujeres (p=0,0001 y p=0,011, respectivamente). Conclusión: Los resultados del presente estudio demuestran que los jóvenes adultos del sexo masculino, atletas y no atletas, presentan mayores niveles de DMO que sus pares del sexo opuesto. Además, los resultados sugieren que, cuando practicado con objetivo competitivo y con volumen de entrenamiento semanal igual o superior a 12 horas, la natación puede ser benéfica para el desarrollo óseo de jóvenes atletas, cuando comparado con el grupo control no atletas. Nivel de evidencia III; Estudio retrospectivo comparativo.

Body composition among long distance runners

SUMMARY OBJECTIVE The current study aimed to examine the body composition of adult male ultra-trail runners (UTR) according to their level of participation (regional UTR-R, vs. national UTR-N). METHODS The sample was composed of 44 adult male UTR (aged 36.5±7.2 years; UTR-R: n=25; UTR-N: n=19). Body composition was assessed by air displacement plethysmography, bioelectrical impedance, and dual-energy X-ray absorptiometry. In addition, the Food Frequency Questionnaire (FFQ) was applied. A comparison between the groups was performed using independent samples t-test. RESULTS Significant differences between groups contrasting in the competitive level were found for chronological age (in years; UTR-R: 38.8±8.2 vs. UTR-N: 33.5±4.1); body density (in L.kg-1; UTR-R: 1.062±0.015 vs. UTR-N: 1.074±0.009); and fat mass (in kg; UTR-R: 12.7±6.8 vs. UTR-N: 7.6±2.7). CONCLUSION UTR-N were younger, presented higher values for body density, and had less fat mass, although no significant differences were found for fat-free mass. The current study evidenced the profile of long-distance runners and the need for weight management programs to regulate body composition.

RESUMO OBJETIVO O presente estudo objetivou examinar a composição corporal dos corredores de ultra-trail (UTR) e, adicionalmente, comparar dois grupos de acordo com o nível de participação (Regional vs. Nacional, respectivamente UTR-R e UTR-N). MÉTODOS A amostra foi composta por 44 corredores adultos masculinos (36,5±7,2 anos de idade; UTR-R: n=25; UTR-N: n=19). A composição corporal foi avaliada recorrendo à pletismografia de ar deslocado, bioimpedância elétrica e absorciometria de raios X de dupla energia. Adicionalmente, foi utilizado o Questionário de Frequência Alimentar. A comparação entre grupos foi realizada com base na prova t-student para amostras independentes. RESULTADOS Foram encontradas diferenças significativas por nível de competição para as seguintes variáveis dependentes: idade cronológica (em anos; UTR-R: 38,8±8,2 vs. UTR-N: 33,5±4,1); densidade corporal (em kg/L; UTR-R: 1,062±0,015 L/kg vs. UTR-N: 1,074±0,009); massa gorda (em kg; UTR-R: 12,7±6,8 kg vs. UTR-N: 7,6±2,7). CONCLUSÃO Os UTR-N tendem a ser mais jovens e apresentam valores superiores de densidade corporal e, consequentemente, valores menores de massa gorda, sendo a massa isenta de gordura semelhante entre os grupos. O presente estudo determinou o perfil dos corredores adultos masculinos de longa distância (ultra-trail), realçando a importância de uma cuidadosa regulação da massa corporal.

Alarm Services as a Useful Tool for Diagnosis and Management of Osteoporosis in Patients with Hip Fractures: A Prospective Observational Multicenter Study

BACKGROUND: Alarm services in the Order Communication System improve awareness for related physicians including orthopaedic surgeons, internal medicine doctors, and other relevent doctors. This prospective observational multicenter study was to compare the diagnostic and treatment rates of osteoporosis between an alarm service group and a no alarm service group.METHODS: From January 2017 to december 2017, The subjects included patients aged 50 years or older with hip fractures from 16 hospital-based multicenter cohorts. Among the 16 hospitals, 5 university hospitals established an alarm service for osteoporosis management (i.e., Alarm group) and 11 university hospitals did not set-up alarm services (i.e., Control group). The rate of dual energy X-ray absorptiometry (DXA) test and the initiation rate of antiosteoporosis medications between the 2 groups were compared at enrollment and at 6 months follow-up.RESULTS: During the study period, 1,405 patients were enrolled. The DXA examination rate and initiation rate of osteoporosis treatment between the Alarm group and the Control group were 484 patients (89.8%) vs. 642 patients (74.1%) (P<0.001) and 355 patients (65.9%) versus 294 patients (33.9%) (P<0.001), respectively. At 6 months follow-up, the rate of anti-osteoporosis management between the 2 groups decreased (57.8% vs. 29.4%).CONCLUSIONS: This prospective multicenter study demonstrates that alarm services can improve awareness of physicians, and it resulted in a significantly higher rate of examination of DXA and initiation of anti-osteoporosis medication in the Alram group. Therefore, alarm service is a simple and effective tool to increase anti-osteoporosis management as part of the fractuure liaison service in South Korea.

Avaliação da porcentagem de gordura corporal em um indivíduo com amputação transfemoral bilateral por diferentes métodos: estudo de caso / Evaluation of body fat percentage in individual with bilateral transfemoral amputation by different methods: case study

A amputação predispõe a um risco de alterações na composição corporal, condição que interfere no equilíbrio no uso da prótese, aumenta o cansaço físico e tem como consequência menor rendimento nas terapias físicas. Nesse sentido, é fundamental eleger o método mais apropriado para avaliar a composição corporal. Objetivo: Avaliar a porcentagem de gordura corporal em um indivíduo com amputação transfemoral por diferentes métodos. Método: Trata-se de um estudo de caso de caráter clínico retrospectivo com um participante do sexo masculino, idade 67 anos com amputação transfemoral bilateral por insuficiência vascular, atendido pelo Serviço de Nutrição do Instituto de Medicina Física e Reabilitação do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - IMREA HCFMUSP. Utilizou-se o somatório das dobras cutâneas, absorciometria de raio-X de dupla energia (DXA) e análise de impedância bioelétrica (IB). Resultados: Os dados antropométricos apontaram porcentagem de gordura corporal de 34,3%, a IB 33% e o DXA revelou 37%. Conclusão: Para este caso, sugere-se que na inviabilidade de avaliar a porcentagem de gordura corporal em indivíduos com amputação com o DXA, o somatório das dobras é o método elegível. Estudos futuros são imprescindíveis a fim de estabelecer o método adequado para avaliação da composição corporal de pessoas com amputações bilaterais de membros inferiores, tendo em vista que este resultado contribui para o melhor desfecho clínico de pacientes em processo de reabilitação.

Amputations increase the risk of changes in body composition, a condition that interferes with balance when wearing prosthetics limbs, increases physical tiredness and results in lower performance in physical therapy. As such, it is essential to choose the most appropriate method for assessing body composition. Objective: To evaluate a percentage of body fat of an individual with amputation by different methods and compare the results. Method: This is a retrospective case study of a male amputee, aged 67 years, with bilateral transfemoral amputations due to vascular conditions, who attended treatment at the Nutrition Services of the Physical and Rehabilitation Medicine Institute of the University of São Paulo Medical School General Hospital, Brazil. The study used the sum of skinfold thickness, dual energy X-ray absorptiometry (DXA), and bioelectrical impedance analysis (BIA). Results: Anthropometric data showed a percentage of body fat of 34, 3%, BIA indicated 33%, and DXA revealed 37%. Conclusion: In this case, we suggest that, if it is unfeasible to use DXA to assess the body composition of amputees, skinfold thickness is the most recommended method. Future studies are essential in order to establish the appropriate method for assessing body composition of people with bilateral lower limb amputations, as it contributes to better clinical outcomes of amputee patients undergoing rehabilitation treatment.

Effects of Thyrotropin Suppression on Bone Health in Menopausal Women with Total Thyroidectomy

BACKGROUND: This study examined the change in the trabecular bone score (TBS), areal bone mineral density (aBMD), and osteoporosis in postmenopausal women who underwent thyrotropin (TSH)-suppressive therapy for treating papillary thyroid cancer after a total thyroidectomy procedure. METHODS: We evaluated 36 postmenopausal women who received a total thyroidectomy for papillary thyroid cancer and were undergoing TSH suppressive therapy with levothyroxine. Postmenopausal women (n=94) matched for age and body mass index were recruited as healthy controls. The aBMD and TBS of the lumbar spine were compared between dual energy X-ray absorptiometry (DXA) at baseline and at follow-up after an average of 4.92 years. RESULTS: There was no significant difference in the rate of diagnoses of osteoporosis, osteopenia, or normal bone status between the 2 groups during the baseline DXA evaluation. However, the TBS was significantly lower whereas aBMD did not show significant difference at the time of baseline DXA measurement (1st DXA, 1.343±0.098 vs. 1.372±0.06317, P < 0.001; 2nd DXA, 1.342±0.095 vs. 1.370±0.062, P < 0.001). The TBS and aBMD did not differ significantly between the initial and follow-up DXA images in both groups of TSH suppressive patients and controls. CONCLUSIONS: The average value of TBS and aBMD did not significantly change during the follow-up period. The TSH suppressive therapy was revealed as not a significant factor for the progressive deterioration of bone status during long term follow-up.

Recomendaciones para el uso correcto de densitometría ósea en la práctica clínica. Consenso de la Sociedad Chilena de Endocrinología y Diabetes / Guidelines of the Chilean Endocrinology Society for the correct clinical use of bone densitometry

Osteoporosis is a silent and frequent disease, which increases fracture risk. Approximately half of women and one of five men over 50 years old will suffer an osteoporotic fracture throughout their lives. Dual-energy x-ray absorptiometry (DXA) allows a real bone mineral density (BMD) measurement in different parts of the skeleton and is considered the "gold standard" for quantifying osteoporosis with high accuracy and precision. The Board of the Chilean Society of Endocrinology and Diabetes (SOCHED) required from the Bone Disease Study Group to develop a consensus about the "Correct use of bone densitometry in clinical practice in Chilean population". Therefore, we elaborated 25 questions which addressed key aspects about the indications for a DXA scan, and the details of how to perform and report this test. Since some of the evidence obtained was of low quality or inconclusive, we decided to create a multidisciplinary group of national experts in osteoporosis to develop a consensus in this subject. The group consisted of 22 physicians including endocrinologists, gynecologists, geriatricians, radiologists, rheumatologists and nuclear medicine specialists. Using the Delphi methodology to analyze previously agreed questions, we elaborated statements that were evaluated by the experts who expressed their degree of agreement. The final report of this consensus was approved by the SOCHED board.

Muscular strength and regional lean mass influence bone mineral health among young females / Força muscular e massa magra regional influenciam a saúde mineral óssea entre jovens mulheres / Fuerza muscular y masa magra influencian la salud mineral ósea entre jóvenes mujeres

ABSTRACT Introduction: Strength training is able to stimulate bone tissue metabolism by increasing mechanical stress on the skeletal system. However, the direct relationship is not yet well established among younger women, since it is necessary to describe which strength enhancement level is able to produce effective changes in bone integrity. Objectives: This study analyzed the influence of muscle strength on bone mineral content (BMC) and bone mineral density (BMD) among female college students. Methods: Fifteen women (24.9 ± 7.2 years) were assessed for regional and whole-body composition by dual-energy X-ray absorptiometry (DXA). The one-repetition maximum (1-RM) tests were assessed on flat bench press (BP), lat pulldown (LPD), leg curl (LC), knee extension (KE), and 45 degree leg press (45LP). Linear regression analyzed the relationships of BMC/BMD with regional composition and 1-RM test values. Measures of dispersion and error (R2 adj and SEE) were tested, defining a p-value of 0.05. Results: The mean value of whole-body BMC was 1925.6 ± 240.4 g and the BMD was 1.03 ± 0.07 g/cm2. Lean mass (LM) was related to BMC (R2 adj = 0.86, p<0.01, and SEE = 35.6 g) and BMD (R2 adj = 0.46, p<0.01, SEE = 0.13 g) in the lower limbs (LL). The 1-RM tests in BP were associated with BMC and BMD (R2 adj = 0.52, p<0.01, SEE = 21.4 g, and R2 adj = 0.68, p<0.01, SEE = 0.05 g/cm2, respectively) in the upper limbs, while the 1-RM tests in KE were related to BMC and BMD (R2 adj = 0.56, p<0.01. SEE = 62.6 g, and R2 adj = 0.58, p<0.01, SEE = 0.11 g/cm2, respectively) in the lower limbs. Conclusions: Hence, the 1-RM tests for multi-joint exercises are relevant to the regional BMC/BMD, reinforcing the need to include resistance exercises in training routines with the purpose of improving muscular strength and regional lean mass, thereby ensuring a healthy bone mineral mass. Level of Evidence II; Development of diagnostic criteria in consecutive patients (with applied reference ''gold'' standard).

RESUMO Introdução: O treinamento de força é capaz de estimular o metabolismo do tecido ósseo, aumentando o estresse mecânico sobre o sistema esquelético. No entanto, a relação direta ainda não está bem estabelecida entre as mulheres mais jovens, uma vez que deve ser descrito qual nível de aprimoramento da força é capaz de induzir mudanças efetivas na integridade óssea. Objetivos: Este estudo analisou a influência da força muscular sobre o conteúdo mineral ósseo (BMC) e a densidade mineral óssea (BMD) entre estudantes universitárias. Métodos: Quinze mulheres (24,9±7,2 anos) foram avaliadas quanto à composição regional e corporal através de absorciometria com raios-X de dupla energia (DEXA). Os testes de repetição máxima (1RM) foram avaliados no supino reto (SR), puxada alta (PA), flexão do joelho (FJ), extensão do joelho (EJ) e leg press 45° (LP45). A regressão linear analisou as relações de BMC/BMD com a composição regional e valores dos testes 1RM. As medidas de dispersão e erro (R2 aj e SEE) foram testadas definindo p ≤0,05. Resultados: O valor médio do BMC corporal foi de 1925,6 ± 240,4 g e BMD de 1,03 ± 0,07 g/cm2. A massa magra (MM) foi relacionada ao BMC (R2 aj=0,86, p<0,01 e SEE=35,6 g) e à BMD (R2 aj=0,46, p<0,01, SEE = 0,13 g/cm2) nos membros inferiores (MI). Os testes 1RM no SR associaram-se com o BMC e à BMD (R2 aj=0,52, p<0,01, SEE=21,4 g, e R2 aj=0,68, p<0,01, SEE=0,05 g/cm2, respectivamente) nos membros superiores, assim como os testes 1RM na EJ relacionaram-se ao BMC e à BMD (R2 aj=0,56, p<0,01, SEE=62,6 g, e R2 aj=0,58, p<0,01, SEE=0,11 g/cm2, respectivamente) nos MI. Conclusões: Dessa forma, os testes 1RM para exercícios multiarticulares são relevantes para o BMC/BMD regional, intensificando a necessidade de incluir exercícios resistivos nas rotinas de treinamento com o propósito de melhorar a força muscular e a massa magra regional e, portanto, assegurar uma massa mineral óssea saudável. Nível de Evidência II; Desenvolvimento de critérios diagnósticos em pacientes consecutivos (com padrão de referência "ouro" aplicado).

RESUMEN Introducción: El entrenamiento de fuerza es capaz de estimular el metabolismo del tejido óseo, aumentando el estrés mecánico sobre el sistema esquelético. Sin embargo, la relación directa aún no está bien establecida entre las mujeres más jóvenes, dado que debe ser descrito qué nivel de mejora de la fuerza es capaz de inducir cambios efectivos en la integridad ósea. Objetivos: Este estudio analizó la influencia de la fuerza muscular sobre el contenido mineral óseo (BMC) y la densidad mineral ósea (BMD) entre estudiantes universitarias. Métodos: Quince mujeres (24,9±7,2 años) fueron evaluadas cuanto a la composición regional y corporal a través de absorciometría con rayos-X de doble energía (DEXA). Los tests de repetición máxima (1RM) fueron evaluados en el supino recto (SR), dominada alta (DA), flexión de la rodilla (FR), extensión de la rodilla (ER) y leg press 45° (LP45). La regresión lineal analizó las relaciones de BMC/BMD con la composición regional y valores de los tests 1RM. Las medidas de dispersión y error (R2 aj y SEE) fueron probadas definiendo p ≤0,05. Resultados: El valor promedio del BMC corporal fue de 1925,6 ± 240,4 g y BMD de 1,03 ± 0,07 g/cm2. La masa magra (MM) fue relacionada al BMC (R2 aj=0,86, p<0,01 y SEE=35,6 g) y a la BMD (R2 aj=0,46, p<0,01, SEE = 0,13 g/cm2) en los miembros inferiores (MI). Los tests 1RM en el SR se asociaron con el BMC y a la BMD (R2 aj=0,52, p<0,01, SEE=21,4 g, y R2 aj=0,68, p<0,01, SEE=0,05 g/cm2, respectivamente) en los miembros superiores, así como los testes 1RM en la ER se relacionaron al BMC y a la BMD (R2 aj=0,56, p<0,01, SEE=62,6 g, y R2 aj=0,58, p<0,01, SEE=0,11 g/cm2, respectivamente) en los MI. Conclusiones: De esa forma, los tests 1RM para ejercicios multiarticulares son relevantes para el BMC/BMD regional, intensificando la necesidad de incluir ejercicios resistivos en las rutinas de entrenamiento con el propósito de mejorar la fuerza muscular y la masa magra regional y, por lo tanto, asegurar una masa mineral ósea saludable. Nivel de Evidencia II; Desarrollo de criterios diagnósticos en pacientes consecutivos (con estándar de referencia "oro" aplicado).

Relationship between Regional Body Fat Distribution and Diabetes Mellitus: 2008 to 2010 Korean National Health and Nutrition Examination Surveys

BACKGROUND: The aim of this study was to investigate the association between regional body fat distribution, especially leg fat mass, and the prevalence of diabetes mellitus (DM) in adult populations. METHODS: A total of 3,181 men and 3,827 postmenopausal women aged 50 years or older were analyzed based on Korea National Health and Nutrition Examination Surveys (2008 to 2010). Body compositions including muscle mass and regional fat mass were measured using dual-energy X-ray absorptiometry. RESULTS: The odds ratios (ORs) for DM was higher with increasing truncal fat mass and arm fat mass, while it was lower with increasing leg fat mass. In a partial correlation analysis adjusted for age, leg fat mass was negatively associated with glycosylated hemoglobin in both sexes and fasting glucose in women. Leg fat mass was positively correlated with appendicular skeletal muscle mass and homeostasis model assessment of β cell. In addition, after adjusting for confounding factors, the OR for DM decreased gradually with increasing leg fat mass quartiles in both genders. When we subdivided the participants into four groups based on the median values of leg fat mass and leg muscle mass, higher leg fat mass significantly lowered the risk of DM even though they have smaller leg muscle mass in both genders (P<0.001). CONCLUSION: The relationship between fat mass and the prevalence of DM is different according to regional body fat distribution. Higher leg fat mass was associated with a lower risk of DM in Korean populations. Maintaining leg fat mass may be important in preventing impaired glucose tolerance.

Multispectral X-ray imaging to distinguish among dental materials

PURPOSE: Dual-energy X-ray imaging is widely used today in various areas of medicine and in other applications. However, no similar technique exists for dental applications. In this study, we propose a dual-energy technique for dental diagnoses based on voltage-switching. MATERIALS AND METHODS: The method presented in this study allowed different groups of materials to be classified based on atomic number, thereby enabling two-dimensional images to be colorized. Computer simulations showed the feasibility of this approach. Using a number of different samples with typical biologic and synthetic dental materials, the technique was applied to radiographs acquired with a commercially available dental X-ray unit. RESULTS: This technique provided a novel visual representation of the intraoral environment in three colors, and is of diagnostic value when compared to state-of-the-art grayscale images, since the oral cavity often contains multiple permanent foreign materials. CONCLUSION: This work developed a technique for two-dimensional dual-energy imaging in the context of dental applications and showed its feasibility with a commercial dental X-ray unit in simulation and experimental studies.

Measurement Uncertainty in Spine Bone Mineral Density by Dual Energy X-ray Absorptiometry

BACKGROUND: The purpose of this study was to calculate the measurement uncertainty of the process of bone mineral density (BMD) analysis using dual energy X-ray absorptiometry with traceability. METHODS: Between March 2015 and October 2016, among healthy participants in their 20s and 30s, the study included those who had not taken calcium, vitamin D supplements and steroids and were without a history of osteoporosis, osteopenia and diseases related to osteoporosis. Relational expression of the model was established based on Guide to the Expression of Uncertainty in Measurements and Eurachem and the uncertainty from each factor was evaluated. RESULTS: The combined standard uncertainty was 0.015, while the expanded uncertainty was 0.0298. The factor-specific standard uncertainties that occurred in the process of measuring BMD were 0.72% for the calibration curve, 0.9% for the internal quality control (IQC) using Aluminum Spine Phantom, 0.58% for European Spine Phantom (ESP), and 0.9% for the inspector precision (IP). CONCLUSIONS: The combined standard uncertainty of the spine BMD corrected with ESP was 0.015 when measured at one time and targeting one participant. The uncertainties of the accuracy of the IQC and the IP were higher than that of the other factors. Therefore, there will be a need for establishment of protocols to lower these uncertainties.

INFLUÊNCIA DA COMPOSIÇÃO CORPORAL REGIONAL E TOTAL SOBRE O DESEMPENHO DE NADO E ÍNDICES AERÓBIOS / INFLUENCE OF REGIONAL AND WHOLE-BODY COMPOSITION ON SWIMMING PERFORMANCE AND AEROBIC INDICES / INFLUENCIA DE LA COMPOSICIÓN CORPORAL REGIONAL Y TOTAL EN EL RENDIMIENTO DE NADO Y ÍNDICES AEROBIOS

RESUMO Introdução: Poucos estudos analisaram a contribuição da composição regional de nadadores para o perfil aeróbio, anaeróbio e o desempenho de nado. Objetivo: Verificar a influência da composição corporal regional e total sobre índices da aptidão aeróbia e anaeróbia em nado atado e livre, bem como sobre o desempenho de curta e média duração. Métodos: Onze nadadores (18,0 ± 4,0 anos) foram submetidos a: (1) teste incremental em nado atado, com coleta de gases respiração-a-respiração (K4b2 associado ao novo-AquaTrainerâ); e (2) tempo limite nos desempenhos de 200, 400 e 800 metros de nado livre. A regressão linear entre distância e tempo (d-tLim) empregou o método dos quadrados mínimos. O coeficiente de Pearson (r) averiguou as correlações da composição corporal regional e total com índices da aptidão aeróbica e anaeróbica em nado atado e livre. Resultados: Os valores da massa isenta de gordura (MIG) foram: 61,7 ± 7,4 kg; 7,5 ± 1,1 kg; 28,3 ± 3,7 kg; 22,1 ± 2,5 kg, respectivamente para corpo todo, membros superiores (MS), tronco (T) e membros inferiores (MI). O consumo máximo de oxigênio (VO2max) foi 52,1 ± 5,3 ml×kg-1×min-1, sendo a carga correspondente (iVO2max) de 93,9 ± 12,2 N. O tempo em 200 (132,2 ± 9,7 s), 400 (296,8 ± 17,2 s) e 800 metros (619,5 ± 26,9 s) forneceu velocidade crítica (VC = 1,23 ± 0,06 m×s-1) e capacidade anaeróbica de nado (CNA = 35,8 ± 15,1 m). Observaram-se correlações de iVO2max, CAN e v200m com MIG para MS (r = 0,64; 0,67 e 0,76), porém a MIG para T, MI e corporal demonstraram correlações apenas com v200m (r = 0,75; 0,69 e 0,75) e CAN (r = 0,71; 0,69 e 0,75). Conclusão: Houve, portanto, influência da MIG regional e corporal sobre o desempenho de curta distância e reservas anaeróbias, sendo a MIG-MS também influente sobre a iVO2max, e assim relacionada ao aprimoramento do desempenho de nado.

ABSTRACT Introduction: There have been few studies analyzing the regional body contribution of swimmers for aerobic and anaerobic profiles and swimming performance. Objective: To verify the influence of regional and whole-body composition on aerobic and anaerobic fitness indices in free and tethered swimming, as well as short- and medium-term performance. Methods: Eleven swimmers (18.0 ± 4.0 years old) were submitted to: (1) an incremental test in tethered swimming, with breath-by-breath gas exchange sampling (K4b2 associated with the new-AquaTrainerâ), and (2) timeout while performing the 200, 400 and 800 meter freestyle. Linear regression analysis between distance and time (d-tLim) was performed using the least squares method. Pearson's coefficient (r) was used to test the correlations between regional and whole-body composition and aerobic and anaerobic fitness indices in freestyle and tethered swimming. Results: Mean values for fat free mass (FFM) were: 61.7±7.4 kg; 7.5±1.1 kg; 28.3±3.7 kg; 22.1±2.5 kg, respectively, for the whole-body, upper-limbs (UL), trunk (T) and lower-limbs (LL). Maximal oxygen uptake (VO2max) was 52.1±5.3 ml×kg-1×min-1, and respective load (iVO2max) was 93.9 ± 12.2 N. The timeout in 200 (132.2±9.7 s), 400 (296.8±17.2 s) and 800 meters (619.5±26.9 s) provided critical velocity (CV = 1.23±0.06 m×s-1) and anaerobic swimming capacity (ASC = 35.8±15.1 m). Correlations were observed for iVO2max, ASC and v200m with FFM for UL (r = 0.64; 0.67 and 0.76), but FFM for T, LL and whole body were related only with v200m (r = 0.75; 0.69 and 0.75) and ASC (r = 0.71; 0.69 and 0.75). Conclusion: Regional and whole-body FFM influenced short-term performance and anaerobic reserves; FFM for UL was also related to iVO2max, and was therefore associated with improved swimming performance.

RESUMEN Introducción: Pocos estudios han examinado la contribución de la composición regional de los nadadores para el perfil aerobio, anaerobio y el rendimiento de nado. Objetivo: Verificar la influencia de la composición corporal regional y total sobre índices de aptitud aerobia y anaerobia en nado estacionario y libre, así como sobre el rendimiento de corta y media duración. Métodos: Once nadadores (18,0 ± 4,0 años) fueron sometidos a: (1) test incremental en nado estacionario, con coleta de gases respiración a respiración (K4b2 asociado al nuevo-AquaTrainerâ); y (2) tiempo límite en el rendimiento de 200, 400 y 800 metros en nado libre. La regresión lineal entre la distancia y el tiempo (d-tLim) utilizó el método de los mínimos cuadrados. Se empleó el coeficiente de Pearson (r) para examinar las correlaciones entre la composición corporal regional y total con los índices de capacidad aerobia y anaerobia en el nado estacionario y en el nado libre. Resultados: Los valores de masa libre de grasa (MLG) fueron: 61,7±7,4 kg; 7,5±1,1 kg; 28,3±3,7 kg; 22,1±2,5 kg, respectivamente, para todo el cuerpo, extremidades superiores (ES), tronco (T) y extremidades inferiores (EI). El consumo máximo de oxígeno (VO2máx) fue 52,1 ± 5,3 ml×kg-1×min-1, y la carga correspondiente (iVO2máx) fue 93,9 ± 12,2 N. El tiempo en 200 (132,2 ± 9,7 s), 400 (296,8 ± 17,2 s) y 800 metros (619,5 ± 26,9 s) estableció la velocidad crítica (VC = 1,23±0,06 m×s-1) y la capacidad del nado anaerobia (CNA = 35,8 ± 15,1 m). Se verificaron correlaciones entre iVO2máx, CNA y v200m con MLG de ES (r = 0,64, 0,67 y 0,76), pero la MLG para T, EI y corporal demostraron correlaciones sólo con la v200m (r = 0,75, 0,69 y 0,75) y la CNA (r = 0,71, 0,69 y 0,75). Conclusión: Por lo tanto, hubo influencia de la MLG regional y total en el rendimiento a corto plazo y en las reservas anaerobias, mientras la MLG-ES influye en la iVO2máx y así en la mejora del rendimiento en la natación.

Dual-Energy X-Ray Absorptiometry: Beyond Bone Mineral Density Determination

Significant improvements in dual-energy X-ray absorptiometry (DXA) concerning quality, image resolution and image acquisition time have allowed the development of various functions. DXA can evaluate bone quality by indirect analysis of micro- and macro-architecture of the bone, which and improve the prediction of fracture risk. DXA can also detect existing fractures, such as vertebral fractures or atypical femur fractures, without additional radiologic imaging and radiation exposure. Moreover, it can assess the metabolic status by the measurement of body composition parameters like muscle mass and visceral fat. Although more studies are required to validate and clinically use these parameters, it is clear that DXA is not just for bone mineral densitometry.

IDIOS: An innovative index for evaluating dental imaging-based osteoporosis screening indices

PURPOSE: The goal of this study was to develop a new index as an objective reference for evaluating current and newly developed indices used for osteoporosis screening based on dental images. Its name; IDIOS, stands for Index of Dental-imaging Indices of Osteoporosis Screening. MATERIALS AND METHODS: A comprehensive PubMed search was conducted to retrieve studies on dental imaging-based indices for osteoporosis screening. The results of the eligible studies, along with other relevant criteria, were used to develop IDIOS, which has scores ranging from 0 (0%) to 15 (100%). The indices presented in the studies we included were then evaluated using IDIOS. RESULTS: The 104 studies that were included utilized 24, 4, and 9 indices derived from panoramic, periapical, and computed tomographic/cone-beam computed tomographic techniques, respectively. The IDIOS scores for these indices ranged from 0 (0%) to 11.75 (78.32%). CONCLUSION: IDIOS is a valuable reference index that facilitates the evaluation of other dental imaging-based osteoporosis screening indices. Furthermore, IDIOS can be utilized to evaluate the accuracy of newly developed indices.